Closed Ampoule Filling Machine

Closed Ampoule Filling Machine is uses for filling and sealing of type D pre sterilized closed ampoules. Machine built on principle of slant travel of ampoules while filling and sealing, to take care of vide variation of ampoule neck dimensions, thicknesses of available standard ampoules.

The Filling unit built on Stainless Steel Square pipe frame and totally encompassed with Stainless Steel Coverings, in pleasing matt finish. Further, large opening available at bottom side of the machine for easy cleaning. The pendant type electrical control panel is lifted from machine for ease of operation and safety. Machine is suitable for ampoule filling in pharmaceutical, cosmetic, agriculture and chemical industries.

Salient Features

  • Compact GMP model.
  • Suitable for filling and sealing of type ‘D’ ampoules.
  • All contact parts made from high quality Stainless Steel 316L & other Non-contact parts made from Stainless Steel 304.
  • Minimum change over parts from 1ml to 10ml ampoule size.
  • “No Ampoule – No Filling” system.
  • Ampoule neck centering during gas flushing and filling operations.
  • Possibility of nitrogen gas flushing before, during and after filling.
  • Full accessibility allows easy maintenance.
  • Machine equipped with pre-warming station.
  • Minimum change over time, little maintenance & easy cleaning.

Process Operation

Pre Sterilized D type Ampoule tray can be directly loaded into slant hopper of the machine. The magazine type cassette delivers closed ampoules on moving eccentric ampoule rack in one/two/four/six/eight’s. Ampoule rotating lever rotate the ampoules and extreme pressure of the gas heat the ampoules. Ampoule opening process is done by the manner of pre-heating and opening with the pressure of the gas (LPG + oxygen). During the stoppage of rack sequentially ampoule opening, pre-gassing, filling, post gassing, pre-heating and final sealing is achieved. Filled & sealed ampoules are collected automatically in SS tray in upright position without hand touch.

Technical Specification

Model AFS – 30C  AFS – 55C  AFS – 100C 
Direction of movement Left to right Left to right Left to right
Production Output 15 to 30 Ampoules/Minute
(depends upon ampoule size)
30 to 50 Ampoules/Minute
(depends upon ampoule size)
50 to 100 Ampoules/Minute
(depends upon ampoule size)
No. of Filling Heads Single Two Four
Ampoule Size 1ml to 10ml 1ml to 20ml 1ml to 5ml
Filling Accuracy -±1% -±1% -±1%
Power Supply 0.5 H.P. 1 H.P. 1 H.P.
Electrical Characteristics 220 Volts, Single Phase, 50 Hertz 220 Volts, Single Phase, 50 Hertz 220 Volts, Single Phase, 50 Hertz
Opening & Sealing Gas LPG + Oxygen (O₂) LPG + Oxygen (O₂) LPG + Oxygen (O₂)
Nitrogen Pressure Required: 1kg/Cm² 1kg/Cm² 1kg/Cm²
Oxygen Pressure Required: 1kg/Cm² 1kg/Cm² 1kg/Cm²
LPG Pressure Required: 0.5Kg/Cm² 0.5Kg/Cm² 0.5Kg/Cm²
Overall Dimension 1100mm (L) x 650mm (W)
x 965mm (H)
1200mm (L) x 800mm (W)
x 965mm (H)
1400mm (L) x 1150mm (W)
x 965mm (H)
Net weight 110 Kgs. Approx. 200 Kgs. Approx. 350 Kgs. Approx.
Note: Electrical characteristics can be adjusted as per customer’s domestic power requirements.