Ampoule Filling Machine Made in India

Closed Ampoule Filling Machine

Closed Mouth Ampoule Filler

Closed Ampoule Filling Machine performs filling and sealing of pre sterile type D closed mouth ampoules. This Filler is having one extra station of opening the ampoules before filling operations. Machine having ampoule opening, filling & sealing station to perform opening (drawing), filling and sealing on on common platform. Machine made from high quality stainless steel 316L materials as per cGMP requirements. Single motor synchronize with all the major unit drives and speed port provided for speed adjustments. Having arrangement of nitrogen-flushing mechanism and possesses both the pre and post-nitrogen flushing unit. One of the major benefits of the equipment is the availability of minimum change-over of ampoules. Apart from this, glass tube filler equipment also features an active pre-heating unit for thick glass ampoules.

Machine having flexibility to fill seal ampoules of 1ml to 30ml capacity. Apart from that, machine has a unique filling capacity of 0.5ml to 25ml in single dosing. Operating on the volumetric piston-pumps type filling principle, the device can fill 10 to 250 ampoules per minute. Another unique advantage of this equipment is the availability of the dead-tray. It offers perfect diversion of the sealed and filled ampoules.

The required gases for sealing or filling the ampoules are oxygen and LPG (propane). This state-of-art machine provides optimum flexibility in the preparation of ampoules containing agro-insecticides, veterinary medicines, cosmetic ampoules and several other chemicals. This Adinath range of Filling and Sealing is perfect for all kinds of open-mouth glass ampoules. We are having Closed Mouth Ampoule Filling in Single, Twin (Double/Two), Four, Six and Eight Head Nozzles variants.

Closed Ampoule Filling Features

  • Opening, Filling & Sealing on single platform.
  • Compact cGMP model.
  • Suitable to fill 1ml to 20ml ampoules.
  • Filling contact parts made from heavy grade Stainless Steel 316L materials.
  • Single motor synchronizes with all drives of the unit.
  • Facility of injecting Nitrogen before and after liquid filling.
  • 0.5ml to 25ml filling in single dosing.
  • Designed to fill and seal type B as well as type C open mouth ampoules.
  • Dead tray provided for upright placement of ampoules during collection.
  • Pre warming unit before sealing for perfect sealing of glass.
  • Change of format parts by hand without using any tool.
  • Delicate ampoule rotating unit attached at the ampoule opening and sealing station.
  • Waste tips collector made with the high quality stainless steel.

Closed Mouth Ampoule Filler Operation

Pre Sterile Closed Ampoules are placed onto hopper of the machine from where it has been dropped to travelling rack in one/two/four/eight by format parts. There is specially designed ampoule opening station with burners. Ampoules are placed onto this station where due to flame ampoule mouth get opened up. Further ampoules advanced to nitrogen purging stations where inert gas needles flush nitrogen. Further ampoules moves to filling unit where filling needles discharge preset volume of liquid into ampoules. Then ampoules stop at post nitrogen unit where again nitrogen get flush inside the ampule. After filling of ampoules it reaches to the sealing unit which is having pre warming and sealing stations. Pre warming station is having less pressure flame which make ampoule warm up to sealing process. Specially designed rollers rotates ampoules at sealing unit for perfect sealing of ampoules all around. Sealing unit perform sealing operation of ampoules. At last ampoules get collected onto collection tray of the machine in upright position for further processing.
The machine performs the following operations:

  • Ampoule loading by hopper, star wheel transfers ampoule into transport rack
  • One/Two/Four/Six/Eight ampoules advanced each machine stroke.
  • Centering of ampoules necks during warming, sealing, gas flushing and liquid filling operations.
  • Rotation of ampoules neck during warming and heating station.
  • Elimination of waste ampoule tips by clippers and ejection into a separate container.

Closed Ampoule Filling Machine Specifications

Model AFS-30C AFS-55C AFS-100C AFS-200C
No. of Head Single Two Four Eight
Syringes One Double Four Eight
Ampoule Sizes 1 ml to 30 ml 1 ml to 30 ml 1 ml to 10 ml 1 ml to 20 ml
Filling Speed Up to 25 ampoules/minute Up to 50 ampoules/minute Up to 100 ampoules/minute Up to 200 ampoules/minute
Filling Precison ± 1% ± 1% ± 1% ± 1%
Filling Pump Piston Pump Piston Pump Piston Pump Piston Pump
Burner Gas LPG & Oxygen (O₂) LPG & Oxygen (O₂) LPG & Oxygen (O₂) LPG & Oxygen (O₂)
Nitrogen Arranegment Before & After Filling Before & After Filling Before & After Filling Before & After Filling
Number of Fill Nozzles One Two Four Eight
Number of Nitrogen Nozzles Two Four Eight Sixteen
Number of Opening Burners One Two Four Eight
Number of Sealing Burners Two Four Eight Sixteen
Power Required 0.5 H.P. 1 H.P. 1 H.P. 2 H.P.
Power Voltage 230 Volts, Single Phase, 50 Hertz, 4 Wire System 230 Volts, Single Phase, 50 Hertz, 4 Wire System 230 Volts, Single Phase, 50 Hertz, 4 Wire System 230 Volts, Single Phase, 50 Hertz, 4 Wire System
Contact Parts Made from Stainless Steel 316L Made from Stainless Steel 316L Made from Stainless Steel 316L Made from Stainless Steel 316L
Overall Dimension 1100mm (L) x 950mm (W) x 965mm (H) approx. 1200mm (L) x 800mm (W) x 965mm (H) approx. 1400mm (L) x 1150mm (W) x 965mm (H) approx. 2400mm (L) x 1400mm (W) x 1100mm (H) approx.
* Power voltage can be adjusted as per customer’s domestic power voltage requirements.
* Rights of technical improvements & modification reserved.
* Illustrations & dimensions are shown for information purpose only.